SpyGlass Pharma Completes $90 Million Series C Financing to Advance Novel Treatments for Glaucoma and other Chronic Ophthalmic Diseases

Financing will support multiple US clinical trials of SpyGlass' innovative drug delivery platform

ALISO VIEJO, Calif., July 10, 2023 /PRNewswire-PRWeb/ -- SpyGlass Pharma, a privately-held ophthalmic therapeutics company, announced today closing $90 million in Series C financing. The financing, which was led by RA Capital Management alongside existing investors New Enterprise Associates ("NEA") and Vensana Capital, as well as new investors Samsara BioCapital and Vertex Ventures HC, will enable the company to conduct multiple US clinical trials of SpyGlass' innovative drug delivery platform. The SpyGlass system has the potential to deliver multiple years of medical therapy to address significant unmet needs in glaucoma management as well as other chronic ophthalmic diseases, when implanted at the time of routine cataract surgery.

"The strong support from our investors validates the potential of the SpyGlass drug delivery platform to meet significant unmet needs for ophthalmic patients and their eye doctors. This round of financing puts the SpyGlass program on a clear path towards Phase 1/2 and Phase 3 clinical trials to support US registration," said Patrick Mooney, CEO of SpyGlass Pharma.

"We believe our approach represents a paradigm shift in the treatment of eye diseases, such as glaucoma, with significant advantages compared to currently commercialized therapies," said Dr. Malik Y. Kahook, MD, Co-Founder and President of SpyGlass Pharma. "The efficacy and safety demonstrated from the first-in-human feasibility trial showing 45% mean IOP-lowering in glaucoma patients, with 100% of subjects off all topical medication 9 months after implantation, is remarkable."

"We're thrilled to lead this financing round to advance SpyGlass' platform technology through the next phases of clinical development," said Zach Scheiner, Ph.D., Principal at RA Capital Management. "There remains a huge unmet need for novel technologies that safely address the challenge of patient adherence in treating glaucoma and other chronic eye diseases. SpyGlass has developed an elegant solution and generated impressive nonclinical and first-in-human data that show great promise for improving patient care and treatment outcomes."

ABOUT SPYGLASS PHARMA

SpyGlass Pharma was co-founded by Dr. Malik Y. Kahook, MD and Glenn Sussman. The company is focused on the development of the world's first, IOL-mounted, controlled release drug delivery platform capable of delivering multiple years of therapy. The technology was originally developed in the Sue Anschutz-Rodgers Eye Center of the University of Colorado School of Medicine and spun off campus post Series A funding from New Enterprise Associates. http://www.spyglasspharma.com

ABOUT RA CAPITAL MANAGEMENT

RA Capital Management is a multi-stage investment manager dedicated to company formation and evidence-based investing in healthcare and life science companies developing drugs, medical devices, diagnostics, services, and research tools. The firm's portfolio of private and public companies spans the globe and most therapeutic areas across all stages from discovery through commercialization. We are committed to fostering diversity at RA, in our portfolio companies, and in the broader biotech community. https://www.racap.com

Media Contact

James Dennewill, SpyGlass Pharma, 1 949-284-6904, pr@spyglasspharma.com

SOURCE SpyGlass Pharma